Development of the skull
The skull is a complex structure; its bones are formed both by intramembranous and endochondral ossification. The bones of the splanchnocranium (face) and the sides and roof of the neurocranium are formed by intramembranous (or dermal) ossification, while the bones supporting the brain (the occipital, sphenoid, temporal, and ethmoid) are largely formed by endochondral ossification.
At birth, the human skull is made up of 45 separate bony elements. As growth occurs, many of these bony elements gradually fuse together into solid bone (for example, the frontal bone). The bones of the roof of the skull are initially separated by regions of dense connective tissue called "cranial sutures". There are five sutures: the frontal suture, sagittal suture, lambdoid suture, coronal suture, and squamosal suture. At birth these regions are fibrous and moveable, necessary for birth and later growth. This growth can put a large amount of tension on the "obstetrical hinge," which is where the squamous and lateral parts of the occipital bone meet. A possible complication of this tension is rupture of the great cerebral vein of Galen. Larger regions of connective tissue where multiple sutures meet are called fontanelles. The six fontanelles are: the anterior fontanelle, the posterior fontanelle, the two sphenoid fontanelles, and the two mastoid fontanelles. As growth and ossification progress, the connective tissue of the fontanelles is invaded and replaced by bone. The posterior fontanelle usually closes by eight weeks, but the anterior fontanelle can remain open up to eighteen months. The anterior fontanelle is located at the junction of the frontal and parietal bones; it is a "soft spot" on a baby's forehead. Careful observation will show that you can count a baby's heart rate by observing his or her pulse pulsing softly through the anterior fontanelle.
Pathology
If the brain is bruised or injured it can be life-threatening. Normally the skull protects the brain from damage through its hard unyieldingness, but in some cases of head injury, there can be raised intracranial pressure through mechanisms such as a subdural haematoma. In these cases the raised intracranial pressure can cause herniation of the brain out of the foramen magnum ('coning') because there is no space for the brain to expand; this can result in significant brain damage or death unless an urgent operation is performed to relieve the pressure. This is why patients with concussion must be watched extremely carefully.

Dating back to Neolithic times, a skull operation called trepanation was sometimes performed. This involved drilling holes in the cranium. Examination of skulls from this period reveals that the "patients" sometimes survived for many years afterward. It seems likely that trepanation was performed for ritualistic or religious reasons and not only as an attempted life-saving technique.
Craniometry and morphology of human skulls
Like the face of a living individual, a human skull and teeth can also tell, to a certain degree, the life history and origin of its owner. Forensic scientists and archaeologists use metric and nonmetric traits to estimate what the bearer of the skull looked like. When a significant amount of bones is found, such as at Spitalfields in the UK and Jomon shell mounds in Japan, osteologists can use traits, such as proportions of length, height, width, to know the relationships of population of the study, with living or extinct populations.
The German physician Franz Joseph Gall in around 1800 formulated the theory of phrenology, which attempted to show that specific features of the skull are associated with certain personality traits or intellectual capabilities of its owner. This theory is now considered to be obsolete.
The practice of craniometry has occasionally purported to reliably demonstrate racial or ethnic differences between skulls of different people. Occasionally this has been used as justification for ideas of racial supremacy. However, this theory is again obsolete.
Sexual dimorphism
In general, male skulls tend to be larger and more robust than female skulls, which are more gracile. Male skulls typically have more prominent supraorbital ridges, a more prominent glabella, and more prominent temporal lines. Male skulls on average have larger, broader palates, squarer orbits, larger mastoid processes, larger sinuses, and larger occipital condyles than those of females. Male mandibles typically have squarer chins and thicker, rougher muscle attachments than female mandibles.

All of these features vary considerably within human populations, making it difficult to identify the sex of a skull without knowledge of the population it came from. The pelvis is considered the best skeletal indicator of sex, due to the fact that the female pelvis must allow for a baby to exit.
Ancestry
Although persons' descents are occasionally stereotyped as different from other ethnic groups on the basis of a variety of traits like eye, hair and skin color, all such characters are not discrete nor preserved in bones. Among archaeologists and forensic scientists, it is still sometimes stated that the most consistent and unique trait of ancestry in skeleton is skull shape (see craniometry).
occipital bone: Foramen magnum | Squama occipitalis (Inion | Nuchal lines | Planum occipitale | Planum nuchale | Cruciform eminence | Internal occipital protuberance | Sagittal sulcus | Internal occipital crest)
Lateral parts (Hypoglossal canal | Condyloid fossa | Condyloid canal | Jugular process | Jugular tubercle) | Basilar part (Pharyngeal tubercle)
parietal bone: Parietal eminence | Temporal line | Parietal foramen
frontal bone: Squama frontalis (Frontal suture | Frontal eminence | Superciliary arches | Glabella | Supraorbital foramen | Zygomatic process | Sagittal sulcus | Frontal crest | Foramen cecum)
Pars orbitalis (Frontal sinus | Frontonasal duct)
temporal bone: Squama temporalis (Articular tubercle | Suprameatal triangle | Mandibular fossa | Petrotympanic fissure) | Mastoid portion (Mastoid foramen
Mastoid process | Mastoid notch | Occipital groove | Sigmoid sulcus | Mastoid antrum)
Petrous portion (Hiatus of the facial canal | Internal auditory meatus | Subarcuate fossa | Carotid canal | Aqueduct of cochlea | Jugular fossa | Inferior tympanic canaliculus | Mastoid canaliculus | Styloid process | Stylomastoid foramen | Petrosquamous suture) | Tympanic part (Suprameatal spine) | Zygomatic process
sphenoid bone: Sphenoidal sinuses | Ethmoidal spine | Optic foramen | Sella turcica | Fossa hypophyseos | Dorsum sellae | Posterior clinoid processes | Carotid groove | Lingula sphenoidalis | Sphenoidal conchæ | Great wings (Spina angularis | Foramen rotundum | Foramen ovale | Foramen Vesalii | Foramen spinosum | Infratemporal crest | Sulcus tubae auditivae | Small wings | Superior orbital fissure | Anterior clinoid process | Optic foramen)
Pterygoid processes (Pterygoid fossa | Scaphoid fossa | Lateral pterygoid plate | Medial pterygoid plate | Pterygoid hamulus | Sphenoidal conchæ | Sphenoidal sinuses)
ethmoid bone: Cribriform plate | Crista galli | Perpendicular plate | Labyrinth | Ethmoid sinus | Uncinate process | Middle nasal concha | Superior meatus | Superior nasal concha | Middle meatus